Germany is in second place, with citizens able to visit 158 countries without obtaining a visa first, while Sweden and South Korea are tied in third place.
The rankings from the worldwide finance firm Arton Capital had US passports tied for sixth place - along with Ireland, Canada, and Malaysia - for global mobility.
The index was developed by Canada-based global residence and citizenship advisory firm Arton Capital.
"This is a testament of Singapore's inclusive diplomatic relations and effective foreign policy", said Philippe May, managing director of Arton Capital's Singapore office. With a visa-free score of 159, the Singapore passport has been certified the world's most powerful in the passport index by global financial advisory firm Arton Capital.
India, figures at 75th position with a visa-free score of 51.
The index takes into account 193 countries and six territories.
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The report showed other countries as follows: Algeria (46); Liberia, Angola, Equatorial Guinea, and Burundi and Cameroon (47) are African countries with a stronger passport than Nigeria. This was the first time that an Asian country has topped the global ranking.
The vote came after Trump refused to allow visa-free travel to members of five European Union countries: Croatia, Cyprus, Poland, Romania and Bulgaria.
But the least powerful passports in the world are Somalia, Syria, Pakistan and Iraq - and Afghanistan is bottom of the list, with a VFS score of just 22 and a rank of 94.
The Nomad Passport Index, meanwhile, ranks 199 citizenships on five factors: visa-free travel, global taxation, perception, dual citizenship and personal freedom.
The most powerful passport has been revealed.
In fact, the United Kingdom passport is only joint-fourth - along with Denmark, Finland, Italy, France, Spain, Norway and Japan.