Jurgen Klopp's side surrendered a three-goal lead in midweek as they drew 3-3 in Spain with Sevilla in the Champions League and the Reds boss will want his men to show no mental scars against the Blues.
What is interesting is Klopp's decision to leave out Roberto Firmino and Sadio Mane from the starting eleven, both of whom finding themselves on the bench in such a high-pressure match.
Mignolet offered a variety of opinions about his Liverpool team-mates during the interview, referring to Philippe Coutinho as the top "player's player", calling Jon Flanagan the team's main jokester, hailing Daniel Sturridge's dance moves and shaming Adam Lallana's as the Anfield teacher's pet.
Following the final whistle, it appeared clear that Mane was keen to voice his frustrations toward Klopp, with footage emerging of words being exchanged between the two.
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The Senegal worldwide was visibly upset with Klopp at the end of the match with the Liverpool boss claiming it was due to an on-field disagreement the pair had. "But no player's happy about that when you come on to the pitch with three minutes left and you feel like you've got 150 minutes in your legs already", Klopp was quoted as saying by the Daily Mirror. (Reuters) Klopp said there was confusion over Mane's position.
Klopp wants his players to make their mark in what he called "the most intensive" stretch of the season.
'Everything is now sorted immediately'.
Perhaps this one should have been left to the dressing room.