Fresh from overseeing an outright record for successive Premier League victories - 15 and counting this season - with another 4-0 masterclass at Swansea City, Guardiola sounded nearly affronted at the idea the leaders might lose their focus.
A double from David Silva and goals from Kevin De Bruyne and Sergio Aguero gave City a comfortable 4-0 win against the league's bottom side, and took their Premier League goals tally to 52 for the season.
"But we are the first ones to win 15 in a row".
Guardiola now holds the record for most consecutive wins in the top-flight of Spanish, German and English soccer with Barcelona, Bayern Munich and Man City respectively.
City's previous best run came as they finished Premier League runners-up to Chelsea despite winning their final six games of the 2014-15 campaign.
Yet the rotation made no difference to unbeaten City's relentless rhythm as they clocked up their 16th victory in 17 league matches this season, with only Everton having taken a point from them.
After seeing off Manchester United on Sunday in their biggest game of the season to date to move 11 points clear at the top, there was barely a hint of a hangover from the Old Trafford victory or the controversial celebrations that followed.
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David Silva ran the game from midfield and scored a goal in each half at Liberty Stadium, with City manager Pep Guardiola describing the Spain playmaker as an "animal".
Three days after beating Manchester United, there was no derby hangover from City. Because of what those three points points mean for their title resume, and because of how an even misfiring City team can still go into their only ostensible title rival's house and beat them at a canter, this latest derby was huge for the victors, the singular inflection point after which we can stop pretending like a title race exists.
"There are a lot more tasks waiting for us, especially I think in December because of all the games".
"We are so demanding for our players".
"Until now we have been able to show we can do things on the European stage, but that is in the past", said Guardiola. We are very happy.
Liverpool are fifth on goal difference after a 0-0 draw at home to dogged West Bromwich Albion at Anfield.
The game began at a terrific pace and the first chance fell to Aguero on five minutes as he weaved his way through two challenges and fired into the side-netting.