Interior Minister Wais Barmak said that 103 people were killed and 235, including 30 policemen, were injured.
US President Donald Trump has called for "decisive action" against the Taliban terrorist group by "all countries" in Afghanistan following yet another terror bombing in the country's capital Kabul that killed at least 95 people.
Saturday's attacker made it through one security checkpoint by driving an ambulance and claiming to be taking a patient to a hospital, the Interior Ministry's deputy spokesperson Nasrat Rahimi told The Associated Press. "He passed through the first checkpoint saying he was taking a patient to Jamuriate hospital and at the second checkpoint he was recognised and blew his explosive-laden auto".
They are a militant group, affiliated to the Taliban, who were responsible for the kidnapping of an American-Canadian family who were freed after five years in captivity. He also urged the worldwide community to "take further action" against state-sponsored "terrorism". He said he didn't know yet if any of their members are wounded or killed.
Trump has said he wanted to shift from a time-based approach in Afghanistan to one based on conditions on the ground.
The government declared a day of mourning, with shops closed and flags at half-staff.
There was global outcry too, with North Atlantic Treaty Organisation, the USA embassy in Kabul and British Foreign Secretary Boris Johnson among those expressing horror at the latest attack.
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The cease-fire ended a two-month escalation between government forces and rebels in the Eastern Ghouta region. Nasr al-Hariri from the SNC said that the next two days would be "a real test for all the sides".
Taliban spokesman Zabiullah Mojahid claimed responsibility for the attack, which comes a week after militants stormed a Kabul hotel.
On Wednesday a USA drone slammed into Pakistani tribal territory that borders Afghanistan killing two Haqqani commanders, according to Pakistani officials, who deny providing organized camps for their safety.
For hours after the blast, plumes of smoke rose from buildings, glass was shattered for blocks around, cars sat in charred heaps and ambulance sirens wailed.
The explosion happened Saturday near diplomatic and government buildings.
Afghan government forces have struggled to fight the Taliban and other militant groups since USA and North Atlantic Treaty Organisation troops formally ended their combat mission in 2014.
Earlier this week on Wednesday, "Save The Children" organisation in Afghan's Jalalabad city, Nangarhar province attacked. They have also blamed the deteriorating security situation on a deeply divided government embroiled in political feuding that has paralyzed Parliament.
United States President Donald Trump has called for "decisive action" by all countries against the terror outfit Taliban after the suicide vehicle bombing in Kabul claimed 95 lives and wounded 163 others.