India folded for 139 in 19.2 overs collapsing to their worst-ever defeat by 80 runs in the first T20 global.
Seifert made his ODI debut in January, when New Zealand rested regular keeper Tom Latham for the home series against Sri Lanka.
New Zealand handed out India a hammering in the first T20I, crushing them by 80 runs - India's worst defeat in the shortest format of the game. "I've been picked for some reason and I just backed myself", man of the match Seifert said.
"It was a great way to start the series and the boys are really happy".
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Seifert reached his maiden T20I half-century from 30 balls and after he and Williamson were dismissed, Ross Taylor (23) and Scott Kuggeleijn (20no) got New Zealand up to 200 and beyond. Stand-in captain Rohit Sharma would like to break these three records in the first T20I if he gets going with the bat.
Shikhar Dhawan blazed away with a quick 29, but five wickets fell for 26 runs in 33 deliveries once he was bowled by Lockie Ferguson.
Mitchell Santner and Ish Sodhi picked four wickets between them, both of them striking twice in an over to break India's backbone. MS Dhoni top-scored for India with 39 runs off 31 balls while no other batsman managing to impress much with the willow.
"Fantastic performance all around, everyone rose and it was one of those complete performances that you search for".
The Kiwis were sitting pretty at 86/0 after eight overs as the Indian bowlers were looking hapless. The home team was earlier routed 4-1 in the five-match One-day global series.