The biggest concern for tornado development is on Saturday afternoon and evening, as the potent piece of energy slides eastward into Louisiana, clashing with a very strong inflow of moist and unstable tropical air from the Gulf of Mexico.
According to the city, damage to buildings and homes were reported and widespread power outages are reported.
A tornado was reported in the area 140 miles (225 kilometres) southwest of Memphis, Tenn., at the time.
A deadly storm system is threatening millions of Americans as severe weather now bears down on the East Coast and parts of the Midwest.
The Robertson County Sheriff's Office said that the tornado was spotted near FM 485, 1644, and FM 46.
The main time frame is from approximately 4 p.m. until 2 a.m.; earlier time west of I-55, then later farther east as storms moves across the state.
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"It looks like a storm came up through Louisiana and into MS and exploded in Monroe County", Monroe County Sheriff Cecil Cantrell said.
The storms most capable of producing tornadoes and large hail will be the individual, rotating cells that form ahead of a larger complex of thunderstorms. Franklin is about 125 miles (200 kilometers) south of Dallas.
There were multiple confirmed fatalities and multiple injuries in Monroe County from severe weather overnight, the Mississippi Emergency Management Agency said without providing any additional details.
A preliminary damage survey found that a tornado with peak intensity of EF-3 and winds up to 140 miles per hour touched down in Robertson County, according to the National Weather Service in Fort Worth.
In Hamilton, Mississippi, 72-year-old Robert Scott said he had been sleeping in his recliner late Saturday when he was awakened and found himself in his yard after a tornado ripped most of his home off its foundation. Crews will continue to survey the damage over the next few days. Some people had to be extricated from their homes.
Meteorologist Monique Sellers said they've received reports of downed trees, as well as damage to buildings and a transmission tower.