Much of Britain hoped their very own Jo Konta would be lining up today, but alas she was removed by Czech teenager Vondrousova. And her backhand - it ought to come with a government health warning.
Scarier still is the thought that all of this could have happened previous year. After Roland Garros, next week she will make her Top 5 singles debut. If she does match her idol and win her maiden grand slam, she will be ranked around the No 13 mark. Although that level wasn't there today for the whole match necessarily, it was there when I needed it. "Oh, it's incredible", she said.
"I can't believe it".
"Here is honestly larger than I could well maybe ever have requested for", she stated. I knew I had to do something different.
In only 68 minutes, Anisimova played aggressive tennis and in the process became the youngest French Open semi-finalist since 17 year-old Nicole Vaidisova of the Czech Republic reached the semifinals of the 2006 French Open before losing to Svetlana Kuznetsova of Russian Federation.
Anisimova's parents moved from Moscow to the United States in order to help the career of their elder daughter, Maria.
Vondrousova agreed. She said of Konta, "She has great form and it's going to be a tough match, but we'll see".
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However, when she was asked about playing on one court or the other, Anisimova said "it doesn't really matter" to her. "They're all attractive courts". The four women who have played so well and made it this far have earned their right to play on the biggest stage. She's pushing the ball really deep.
"It was cold and windy and I can't wait to enjoy it, it's been an fantastic journey I have been on and I can't wait until tomorrow".
The field quantity 51 will face Australian eighth seed Ashleigh Barty, who beat American Madison Keys 6-3 7-5. Barty forced a tiebreak, which Anisimova won.
Ms Barty is already guaranteed a minimum of $1.9 million AUD in prize money and if she wins, she will take home $3.7 million.
Barty took a break from professional tennis as a teenager after finding the pressure too much and spent a spell playing professional cricket, and this is the most remarkable chapter yet in her comeback.
"I haven't played against her", Barty said.
"It's an opportunity for all four of us to go out there and try to continue that". It's just an incredible situation to be in.
Assessing her performance, Barty added: "I played some really good tennis".